Loxagyl Suspension (Pediatric) x60ml

Loxagyl Suspension (Pediatric) is a targeted antimicrobial medication containing Metronidazole 200mg. Specifically formulated for children, this suspension effectively combats anaerobic bacterial infections and certain protozoal infections with a palatable taste for improved compliance.

Uses

Loxagyl Suspension (Pediatric) effectively treats various infections in children, including anaerobic bacterial infections, amoebiasis (intestinal and liver), giardiasis, bacterial vaginosis, dental and oral infections, intra-abdominal infections, and prevention of post-surgical infections.

Benefits

• Targeted treatment for anaerobic bacterial infections
• Effective against protozoal parasites
• Child-friendly suspension form
• Convenient dosing schedule
• High bioavailability
• Penetrates tissues effectively
• Broad spectrum of antimicrobial activity
• Reduces risk of surgical site infections when used prophylactically

How It Works

Loxagyl Suspension works through a sophisticated mechanism of action. Once absorbed, Metronidazole enters bacterial cells and protozoa where it is converted into active compounds. These compounds disrupt DNA and inhibit nucleic acid synthesis, preventing microbial replication and ultimately leading to the death of the infectious organisms.

Duration of Action

The medication typically remains active in the body for 6-8 hours after administration. Peak plasma concentrations occur within 1-2 hours of dosing, with a half-life of approximately 8 hours in children with normal liver function.

Dosage

Warnings

Discontinue Loxagyl Suspension and seek immediate medical attention if the child experiences seizures, neurological symptoms, severe allergic reactions, or unusual bleeding. The medication may cause a harmless darkening of urine. Avoid alcohol-containing foods or medicines during treatment.

Side Effects

Potential side effects may include nausea and vomiting, metallic taste, mild stomach discomfort, diarrhea or constipation, loss of appetite, and temporary neutropenia.

Pregnancy and Breastfeeding

Not applicable for this pediatric formulation. However, Loxagyl Suspension should not be administered to nursing mothers as Metronidazole passes into breast milk and may affect the nursing infant.

Interactions

• Warfarin and other anticoagulants (increased bleeding risk)
• Phenobarbital and phenytoin (reduced Metronidazole effectiveness)
• Lithium (increased lithium toxicity risk)
• Disulfiram (may cause psychotic reactions)
• Cimetidine (may increase Metronidazole levels)
• Oral contraceptives (potential reduced effectiveness)

Precautions

Complete the full prescribed course. Administer with food to reduce stomach upset. Shake well before each use. Store at room temperature protected from light. Regular monitoring for children on prolonged therapy. Avoid long-term use without medical supervision.

Important Information

Loxagyl Suspension (Pediatric) is an effective antimicrobial medication specifically formulated for children. The pleasant-tasting suspension ensures better compliance while delivering the therapeutic benefits of Metronidazole 200mg. This medication should be administered under proper medical supervision with dosage adjusted based on the child’s weight and specific infection.